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Should note that context may be key here.
For example, a recent meta-analysis shows that the efficacy of exercise appears to be superior to metformin in prediabetes, but metformin appears to be superior to exercise in patients with type 2 diabetes.
And the combination of exercise + metformin is efficacious for glucose control in both diabetes/prediabetes.
14.8. klo 01.06
Exercise outperforms medication in diabetes management.
The largest study ever on diabetes prevention showed a lifestyle intervention with 150 minutes of weekly moderate-intensity exercise cut diabetes incidence by 39%, surpassing Metformin's effect.
A 20-year follow-up revealed a 24% reduction in diabetes incidence and a 3.5-year increase in diabetes-free survival for the exercise group, compared to 17% and 2.5 years for Metformin.
This shouldn't be surprising. Even light exercise significantly improves blood glucose control and mitochondrial function, making movement unmatched for metabolic health.
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