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Dr. Aseem Malhotra & Gary Brecka discuss statin research & cholesterol in this 3:18 clip:
- Malhotra cites John Ioannidis (Stanford, most-cited medical researcher): Greater financial interests in a field → higher chance findings may not hold up
- Statins: Most prescribed for primary prevention (no prior heart event) — industry trials show ~1 in 100 benefit (non-fatal event prevention) over 5 years, no life extension in best-case scenario
- He emphasizes sharing this with patients for informed decisions
- Both note: When adjusting for triglycerides/HDL (tied to insulin resistance), LDL alone is not an independent risk factor for heart disease
- In older adults (>60), higher LDL correlates with greater longevity (potential immune role)
Clip here — thoughtful conversation on statin evidence & cholesterol views 👇
What do you think about financial influence on medical research?
Or how should patients weigh benefit stats like 1 in 100?
Honest thoughts — no judgment.
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